An aspirin allergy or hypersensitivity is a common type of allergy that disproportionately affects people with asthma. For those people that rely on the medication for their treatment, aspirin desensitization can reduce health risks and offer long-term relief. And with the threat of severe allergic reactions like anaphylaxis, those most at risk must take aspirin allergies seriously. Here are the main factors Atlanta patients should know about aspirin desensitization.
What Is Aspirin Sensitivity?
While some people are allergic to aspirin, most people will have a sensitivity to the drug rather than an “allergy.” A sensitivity is not a true allergy though the symptoms are similar, and both aspirin sensitivity and aspirin allergies carry a health risk. Some of the common symptoms of aspirin sensitivity include:
- Skin rash or hives
- Runny nose or congestion
- Shortness of breath
- Wheezing
Data suggests that aspirin sensitivity affects around 1% of the population, with less-severe aspirin intolerance affecting approximately 20%.
What Is Aspirin Desensitization?
Aspirin desensitization is a tolerance-building treatment for aspirin-exacerbated respiratory disease (AERD). AERD is a chronic condition that includes asthma, sinus disease with recurrent nasal polyps and sensitivity to aspirin. People with sensitivity to aspirin usually also have a sensitivity to nonsteroidal anti-inflammatory drugs (NSAIDs).
The desensitization process takes place over two to three days at an allergist’s office. Patients start by receiving either a dose of aspirin or an NSAID nasal spray. The dosage is gradually increased until some minor symptoms are identified. Patients will then continue with this dose until tolerance is developed. Eventually, patients will reach a target dose without experiencing any signs of sensitivity.
Subsequent to treatment, individuals are required to take a dose of aspirin each day at home to support their tolerance to the drug. This additional step ensures the desensitization results are maintained, while also reducing the risks of asthma symptoms and developing nasal polyps.
Cross-Reactivity Between Aspirin and NSAIDs
Many people experience cross-reactivity between aspirin and NSAIDs such as ibuprofen and naproxen sodium. This cross-reactivity means that desensitization to aspirin will also produce desensitization to NSAIDs. For patients whose treatment requires taking various medications, becoming desensitized to multiple drugs enhances their therapy options – and reduces the chances of severe reactions.
How Effective Is Aspirin Desensitization?
Aspirin desensitization has been found to be a safe and effective AERD treatment. In addition, desensitization is also valuable as an asthma treatment for AERD-affected patients. One study found that six months of treatment delivered benefits for asthma patients with AERD, with participants experiencing a significantly improved quality of life with reduced symptoms.
Professional Atlanta Area Aspirin Desensitization Treatment
Chacko Allergy, Asthma and Sinus Center helps patients with AERD and other related conditions. To discuss aspirin desensitization treatment, visit one of our centers in Alpharetta, Atlanta, Canton, Cumming, Druid Hills, Duluth and Johns Creek. For assistance, call (678) 668-4688 or make an appointment now.
